Experimental application of our vaccination
system on Dicentrarchus lambrax
(sea bass), a fish of rising economic
relevance in the aquaculture of Mediterranean
countries, was carried-out near Abruzzo
and Molise Zoo-prophylactic Institute.
Fish model: sea bass
of approximately 2 g (100 sea bass/group)
Vaccine: formalin- inactivated
Photobacterium damsela subsp. piscicida
(Phdp) loaded MS
Encapsulation efficiency (FITC-labeled
Phdp): 23 % w/w.
40 days after the treatment, an experimental
infection was induced by by i. p.
injection bacterial suspensions: mortality
was monitored throughout follow-up
of 14 days.
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CONCLUSIONS.
This oral vaccination microsystem is
as effective or more effective than
the immersion method, chosen as the
elective way commonly used for fish
of these size. Besides, this result
was obtained using an oral vaccine with
a bacterial cells concentration 10-times
lower than used for immersion vaccination.
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