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H I T S
 on anticancer metal-based compound discovery

                                LATEST ISSUES
Ruthenium-Based Staurosporine Mimics with Anticancer Activity
By E. Meggers et al., Cancer Research 2007; Meggers Laboratory at the Phillips-University of Marburg (Germany).
KP1019 alters the mitochondrial membrane potential and induces apoptosis
By BK Keppler et al., 2004-2005
First clinical study with RUTHENIUM complexes: A Phase I study with NAMI-A
Selected data from Clin. Cancer Res., 10:3717-3727, 2004
Intra tumour NAMI-A treatment: CD44 regulation, TIL recruitment and metastasis reductions
by S. Pacor et al.; selected data from JPET 310:737-744, 2004
F-actin distribution in NAMI-A treated HeLa cells scanning electron microscope appearance of HeLa cells after NAMI-A treatment
by G. Sava, selected data from European Journal of Cancer, 40: 1383-1396, 2004
Selective binding of NAMI-A to lung collagen and around metastases
by G Sava et al., Clinical Cancer Research 9: 1898-1905, 2003
NAMI-A inhibits VEGF-induced angiogenesis in rabbit cornea
by L Morbidelli et al., British Journal of Cancer 88: 1484-1491, 2003

NAMI-A inhibits angiogenesis in vivo in the CAM model
by Vacca A et al., University of Bari, Italy

NAMI-A prevents ERK phosphorilation and inhibits c-myc expression in ECV304 cells
by Pintus et al., University of Sassari, Italy
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