| Friday
12 |
| 13:00-15:00 |
|
Registration |
| 15:00-15:30 |
|
Opening:
Chairman COST D20 + local representatives |
15:30-18:30
Chairman:B. Lippert |
PL |
15:30-16:20
Michael J. Clarke
Merkert Chemistry Center, Boston College, MA, USA
Historical Perspective of Ruthenium Anticancer Agents |
| |
PL |
16:20-17:10
Silvio Aime
University of Torino, Italy
Paramagnetic Lanthanide Chelates in MRI: from Extracellular
Contrast Agents to Probes for Molecular Imaging |
| |
WG
0001 |
17:10-17:15
Enzo Alessio
University of Trieste, Italy
Overview on Working Group 0001 |
| |
|
17:15-18:00
Peter J. Sadler
School of Chemistry, University of Edinburgh, Edinburgh,
UK
Design of Novel, Innovative Metal Anticancer Drugs |
| |
|
18:00-18:15
Ana Maria Pizarro
Universidad Autónoma de Madrid, Madrid, Spain
Novel Aqueous Chemistry of a transDiamine Anticancer
Complex |
| |
|
18:15-18:30
Vladimir Kokozay
National Taras Shevchenko University, Kyiv, Ukraine
Direct Synthesis of Bioactive Heterobimetallic Complexes |
| 20:00 |
|
Welcome
reception in the Caffè Tommaseo |
| Saturday
13 |
08:45-10:40
Chairman:G. Natile |
WG
0002 |
08:45-09:35
Helmut Sigel
University of Basel, Basel, Switzerland
Overview on Working Group 0002 + Metal Ion Complexes of Nucleic
Acid Constituents with Potentials in Antiviral and Anticancer
Therapy |
| |
WG
0003 |
09:35-10:25
Viktor Brabec
Academy of Science of the Czech Republic, Brno, Czech
Republic
Overview on Working Group 0003 + Biochemistry, Structural
and Cellular Biology of Non-Classical Antitumor Platinum Compounds |
| |
|
10:25-10:40
Yousef Najajreh
The Hebrew University of Jerusalem, Jerusalem, Israel
Synthesis and Antitumor Activity of Novel trans-Diamminedichloroplatinum(II)
Derivatives. |
| 10:40-11:10 |
|
Coffee
break (included in poster session) |
11:10-12:45
Chairman:N. Katsaros |
WG
0005 |
11:10-11:15
Gianni Sava
University of Trieste, Trieste, Italy
Overview on Working Group 0005 |
| |
|
11:15-12:00
Bernhard K. Keppler
University of Wien, Wien, Austria
Development of Platinum and Non-Platinum Anticancer Compounds |
| |
WG
0002 |
12:00-12:15
Marta Garijo Añorbe
University of Dortmund, Dortmund, Germany
Pt(II)-Acidification of the N(6)H2 Group of Adenines |
| |
WG
0003 |
12:15-12:30
Vivienne Munk
University of Edinburgh, Edinburgh, United Kingdom
Non-Classical Platinum Anticancer Complexes: Role of Redox
Reactions, Coordination Geometry and Steric Effects in Biological
Activity. |
| |
|
12:30-12:45
Olivier Delalande
University of Paris V, Paris, France
Chiral Platinum Complexes Reacting with DNA: Perturbation
of the Double-Helix Studied by NMR, Molecular Modeling, and
Biophysical Methods. |
| 12:45-14:00 |
|
Lunch
at the University Cafeteria |
14:00-16:25
Chairman:E. Sletten |
WG
0005 |
14:00.14:15
Darren Griffith
Royal College of Surgeons, Dublin, Ireland
Hydroxamate Complexes of Ruthenium and Platinum: Synthesis,
Characterisation and Biological Activity |
| |
WG
0006 |
14:15-15:05
Iztok Turel
University of Ljubljana, Ljubljana, Slovenia
Overview on Working Group 0006 + Metal Ion Complexes with
Antibacterial Quinolones and Antiviral Nucleotide Analogues |
| |
|
15.05-15.20
Andres Tasada
University of the Balearic Islands, Mallorca, Spain
New N6,N6'-Polymethylene Bisadenines and their Chelating Properties. |
| |
WG
0007 |
15:20-16:10
Gerard Jaouen
ENSCP, France
Overview on Working Group 0007 + Metal Complexed SERMs (Selective
Estrogen Receptor Modulators). Synthesis and Antiproliferative
Effects. |
| |
WG
0005 |
16:10-16:25
Karlijn van den Schilden
Leiden Institute of Chemistry, Leiden, The Netherlands
Novel Polynuclear Ruthenium and Platinum Complexes and their
Interactions with DNA-Model Bases. |
| 16:25-17:10 |
|
Coffee
break (included in poster session) |
17:10-18:50
Chairman:J. Kozelka |
PL |
17:10-18:00
Nick Farrell
Virginia Commonwealth University, USA
Platinum Anticancer Agents. Structures and Targeted Bio-molecules. |
| |
WG
0009 |
18:00-18:50
Luigi Messori
University of Firenze, Firenze, Italy
Overview on Working Group 0009 + The Interplay of Metallodrugs
and Plasma Proteins |
| 20:30 |
|
Social
dinner at Antica Trattoria Suban |
| Sunday
14 |
09:00-10:40
Chairman:I. Sóvágó |
WG
0010 |
09:00-09:50
Michael J. Hannon
University of Warwick, Coventry, United Kingdom
Overview on Working Group 0010 + Non-Covalent DNA Recognition
and Remarkable DNA Structural Effects Induced by Supramolecular
Cylinders. |
| |
WG
0012 |
09:50-10:40
Rodica-Mariana Ion
Institute for Chemical Research, Bucharest, Romania
Overview on on Working Group 0012 + Chemical Structure - Activity
Correlation in Photodynamic Therapy of Cancer. |
| 10:40-11:10 |
|
Coffee
break (included in poster session) |
11:10-12:30
Chairman:J. Reedijk |
WG
0007 |
11:10-11:25
Stephane Masi
Zurich, Switzerland
New Methods for the Synthesis of CpRe(CO)3 and
CpTc(CO)3 Units from Ferrocene Unit. |
| |
WG
0009 |
11:25-11:40
Christian Hartinger
University of Wien, Wien, Austria
Interaction of Metal Complexes with Biomolecules |
| |
WG
0010 |
11:40-11:55
Jens Müller
University of Dortmund, Dortmund, Germany
Platinum-Modified DNA and PNA Oligomers in Antisense and Antigene
Strategies. |
| |
WG
0005 |
11:55-12:10
Claire S. Allardyce
EPFL, Lausanne,Switzerland
Use of Mass Spectrometry to Help Identify Drug-Protein In-teractions. |
| |
|
12:10-12:30
Concluding remarks |
| 12:30-13:30 |
|
Lunch
at the University Cafeteria |
| 13:30-15:30 |
|
COST D20 MC Meeting + Discussion with Reviewers |
Posters should be hanged the first day (afternoon 12 or morning
13).
Posters should not exceed 100 (width) x 120 (height) cm. Adhesive
material will be available on site. |
