Scientific Director

Gianni Sava, biologist.
E-mails: g.sava@callerio.org - gsava@fc.units.it

Professor of Pharmacology at the University of Trieste. Active in the field of cancer chemotherapy since 1975 (first paper published "GIRALDI T, NISI C, SAVA G. Investigation on the oxidative N-demethylation of aryltriazenes in vitro.Biochemical Pharmacology", 24: 1793-1797, 1975").
Major subjects of expertise include:
a) pharmacological profile of sodium sulphide,
b) antitumour properties of diazo-derivatives of aminoacids, dimethyl-triazenes and metal complexes of group VIII transition metals,
c) immunepharmacology of lysozymes.
Wide experience on the pharmacological characterisation of drugs active on solid tumour metastases. Author or co-author of 216 scientific papers published on specialised journals, serial books or targeted books (updated November 2004) .

Last paper published:"Vock CA, Ang WH, Scolaro C, Phillips AD, Lagopoulos L, Juillerat-Jeanneret L, Sava G, Scopelliti R, Dyson PJ.Development of ruthenium antitumor drugs that overcome multidrug resistance mechanisms." J Med Chem. 2007 May 3;50(9):2166-75. Epub 2007 Apr 10

staff

Moreno Cocchietto, biologist.
E-mails: mcocchietto@fc.units.it - m.cocchietto@callerio.org

Expert in atomic absorption spectroscopy determination of ruthenium compounds in biological fluids and tissues.

Last paper published "Gava B, Zorzet S, Spessotto P, Cocchietto M, Sava G. Inhibition of B16 melanoma metastases with the ruthenium complex imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate and down-regulation of tumor cell invasion" J Pharmacol Exp Ther. 2006 Apr;317(1):284-91. Epub 2005 Dec 20.

staff

Alberta Bergamo, chemist and technological pharmacist.
E-mail: a.bergamo@callerio.org - abergamo@fc.units.it

Expert in flow cytometry analysis of in vitro and ex vivo cell preparations, experience accumulated also during a one-year study at the Laboratoir d'Oncogenèse Immunologique of Nantes (France).

Last paper published "Bergamo A and Sava G. Ruthenium complexes can target determinants of tumour malignancy" Dalton Trans. 2007 Apr 7;(13):1267-72. Epub 2007 Feb 28.

staff

Michele Zabucchi, staff technician.
E-mail: m.zabucchi@callerio.org - michele@fc.units.it

Expert in histology and light transmission microscopy.

on research fellowship

Laura Zorzin, Degree in Chemical and Technological Pharmacy. PhD student. PhD in Pharmacology, Chemotherapy and Microbiology.
E-mail: lallazin@yahoo.it

Thesis work on: Pharmacological effects of lysozyme containing microcapsules for drug oral administrations. Supported by Fondo Sociale Europeo 2003, D4.

on research fellowship

Laura Brescacin, Degree in Chemical and Technological Pharmacy. PhD student. PhD in Pharmacology, Toxicology and Intensive Care.

Thesis work on: TGFb signalling modulation in the antimetastatic activity of ruthenium complexes.

Maria Donata Gori

This lady has left us forever. A sadly ironic demise due to the dreadful thing we are fighting professionally: she died of cancer.
We enjoyed for so many years her company, her co-operation, her ever-helpful attitude, her incredibly human efficiency; then during her disease we shared her hopes and her illusions until the very last moments.
We refuse to remove her name from this page for she still is part of the team: her being here - and in our dearest memories - will remind us daily that the monster we are wrestling against strikes blindly and brutally, and that no effort is to be spared to defeat it.
Donata, we won't forget you.